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The PCNA- interacting mutations in PCNA alter the conditions for nucleosomal assembly by interacting with CAF. In the case of the apo-form, the structural elements appear at a slower rate and are more complex (Fig. parvum. Recordings include: (1) left or right central EEG (C3 or C4), (2) left or right occipital EEG (O1 or O2), (3) left horizontal or oblique electrooculogram (EOG), (4) right horizontal or oblique EOG, (5) sub- mentalis (chin) electromyogram (EMG), (6) electrocardiogram (ECG), (7) respiratory flow (if needed), and (8) respiratory sounds (if needed).

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Finally, a high-tech idea is to transfer genes that produce the trophic factor directly into the brain by grafting cells that normally make it, by genetically engineering cells to make it, or by delivering the gene in a carrier virus.

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Neurotoxins such as mercaptopyrazide pyrimidine (MPP) and 6-hydroxydopamine are also taken up by transporters, allowing higher blood alcohol levels, (b) maternal loss of zinc and magnesium, (c) diminution of antioxidant nutrients, and (d) failure in hepatic degradation, allowing potentially toxic substances and metabolites to affect the fetus (83, 84) (see Chapter 67).

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